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  1. We and others have previously reported that resveratrol (RSV) suppresses colon cancer cell proliferation and elevates apoptosis in vitro and/or in vivo, however molecular mechanisms are not fully elucidated. Part...

    Authors: Jairam Vanamala, Sridhar Radhakrishnan, Lavanya Reddivari, Vadiraja B Bhat and Andrey Ptitsyn
    Citation: Proteome Science 2011 9:49
    Content type: Research Published on:

  2. The anaerobe Clostridium difficile produces two major virulence factors toxin A and B that inactivate Rho proteins by glucosylation of a pivotal threonine residue. Purified toxins induce reorganization of the cyt...

    Authors: Nelli Jochim, Ralf Gerhard, Ingo Just and Andreas Pich
    Citation: Proteome Science 2011 9:48
    Content type: Research Published on:

  3. We have previously constructed an in-depth human glomerulus proteome database from a large amount of sample for understanding renal disease pathogenesis and aiding the biomarker exploration. However, it is usu...

    Authors: Ying Zhang, Yutaka Yoshida, Bo Xu, Sameh Magdeldin, Hidehiko Fujinaka, Zan Liu, Masahito Miyamoto, Eishin Yaoita and Tadashi Yamamoto
    Citation: Proteome Science 2011 9:47
    Content type: Research Published on:

  4. Mineral nutrition during wheat grain development has large effects on wheat flour protein content and composition, which in turn affect flour quality and immunogenic potential for a commodity of great economic...

    Authors: Susan B Altenbach, Charlene K Tanaka, William J Hurkman, Linda C Whitehand, William H Vensel and Frances M Dupont
    Citation: Proteome Science 2011 9:46
    Content type: Research Published on:

  5. Immunoprecipitation and subsequent 2D-PAGE/mass spectrometry are powerful tools to study post-translational protein modifications. Often disregarded in this workflow is the impact of the chemical cross-linker ...

    Authors: Mirta ML Sousa, Kristian W Steen, Lars Hagen and Geir Slupphaug
    Citation: Proteome Science 2011 9:45
    Content type: Methodology Published on:

  6. White leaf No.1 is a typical albino tea cultivar grown in China and it has received increased attention in recent years due to the fact that white leaves containing a high level of amino acids, which are very ...

    Authors: Qin Li, Jianan Huang, Shuoqian Liu, Juan Li, Xinhe Yang, Yisong Liu and Zhonghua Liu
    Citation: Proteome Science 2011 9:44
    Content type: Research Published on:

  7. The similarly in plant physiology and the difficulty of plant classification, in some medicinal plant species, especially plants of the Zingiberaceae family, are a major problem for pharmacologists, leading to...

    Authors: Apaporn Boonmee, Chantragan Srisomsap, Daranee Chokchaichamnankit, Aphichart Karnchanatat and Polkit Sangvanich
    Citation: Proteome Science 2011 9:43
    Content type: Research Published on:

  8. The inflammatory disease periodontitis results in tooth loss and can even lead to diseases of the whole body if not treated. Gingival crevicular fluid (GCF) reflects the condition of the gingiva and contains p...

    Authors: Young-Jin Choi, Sun-Hee Heo, Jae-Mok Lee and Je-Yoel Cho
    Citation: Proteome Science 2011 9:42
    Content type: Research Published on:

  9. Many important molecular events associated with implantation and development occur within the female reproductive tract, especially within the uterus endometrium, during pregnancy periods. The endometrium incl...

    Authors: Jung-Il Chae, Jumi Kim, Seong G Lee, Young-Joo Jeon, Dong-Wook Kim, Yunjo Soh, Kang S Seo, Hak K Lee, Nag-Jin Choi, Joohyun Ryu, Sunghyun Kang, Seong-Keun Cho, Dong-Seok Lee, Hyung M Chung and and Deog-Bon Koo
    Citation: Proteome Science 2011 9:41
    Content type: Research Published on:

  10. Saccharopolyspora spinosa produces the environment-friendly biopesticide spinosad, a mixture of two polyketide-derived macrolide active ingredients called spinosyns A and D. Therefore considerable interest is in...

    Authors: Yushuang Luo, Xuezhi Ding, Liqiu Xia, Fan Huang, Wenping Li, Shaoya Huang, Ying Tang and Yunjun Sun
    Citation: Proteome Science 2011 9:40
    Content type: Research Published on:

  11. The present study focused on comparative proteome analyses of low- and high-temperature stresses and potential protein-protein interaction networks, constructed by using a bioinformatics approach, in response ...

    Authors: Pavinee Kurdrid, Jittisak Senachak, Matura Sirijuntarut, Rayakorn Yutthanasirikul, Phuttawadee Phuengcharoen, Wattana Jeamton, Sittiruk Roytrakul, Supapon Cheevadhanarak and Apiradee Hongsthong
    Citation: Proteome Science 2011 9:39
    Content type: Research Published on:

  13. High temperature is a critical abiotic stress that reduces crop yield and quality. Rice (Oryza sativa L.) plants remodel their proteomes in response to high temperature stress. Moreover, phosphorylation is the mo...

    Authors: Xinhai Chen, Wenfeng Zhang, Baoqian Zhang, Jiechao Zhou, Yongfei Wang, Qiaobin Yang, Yuqin Ke and Huaqin He
    Citation: Proteome Science 2011 9:37
    Content type: Research Published on:

  14. Cervical intraepithelial neoplasia (CIN) grades 2 and 3 are usually grouped and treated in the same way as "high grade", in spite of their different risk to cancer progression and spontaneous regression rates....

    Authors: Kai-Erik Uleberg, Ane Cecilie Munk, Cato Brede, Einar Gudlaugsson, Bianca van Diermen, Ivar Skaland, Anais Malpica, Emiel AM Janssen, Anne Hjelle and Jan PA Baak
    Citation: Proteome Science 2011 9:36
    Content type: Research Published on:

  15. The epidermal growth factor receptor (EGFR) is usually overexpressed in nasopharyngeal carcinoma (NPC) and is associated with pathogenesis of NPC. However, the downstream signaling proteins of EGFR in NPC have...

    Authors: Lin Ruan, Xin-Hui Li, Xun-Xun Wan, Hong Yi, Cui Li, Mao-Yu Li, Peng-Fei Zhang, Gu-Qing Zeng, Jia-Quan Qu, Qiu-Yan He, Jian-Huang Li, Yu Chen, Zhu-Chu Chen and Zhi-Qiang Xiao
    Citation: Proteome Science 2011 9:35
    Content type: Research Published on:

  16. A large variety of proteins involved in inflammation, coagulation, lipid-oxidation and lipid metabolism have been associated with high-density lipoprotein (HDL) and it is anticipated that changes in the HDL pr...

    Authors: Johannes HM Levels, Pierre Geurts, Helen Karlsson, Raphaël Marée, Stefan Ljunggren, Louise Fornander, Louis Wehenkel, Mats Lindahl, Erik SG Stroes, Jan A Kuivenhoven and Joost CM Meijers
    Citation: Proteome Science 2011 9:34
    Content type: Research Published on:

  17. Cytokinin is a plant hormone that plays a crucial role in several processes of plant growth and development. In recent years, major breakthroughs have been achieved in the elucidation of the metabolism, the si...

    Authors: Anne Cortleven, Jean-Paul Noben and Roland Valcke
    Citation: Proteome Science 2011 9:33
    Content type: Research Published on:

  18. Actinobacillus pleuropneumoniae (APP) is one of the most important swine pathogens worldwide. Identification and characterization of novel antigenic APP vaccine candidates are underway. In the present study, we ...

    Authors: Wei Zhang, Jing Shao, Guangjin Liu, Fang Tang, Yan Lu, Zhipeng Zhai, Yang Wang, Zongfu Wu, Huochun Yao and Chengping Lu
    Citation: Proteome Science 2011 9:32
    Content type: Research Published on:

  19. Diagnosis of esophageal squamous cell carcinoma (SCC) may improve with early diagnosis. Currently it is difficult to diagnose SCC in the early stage because there is a limited number of tumor markers available.

    Authors: Akiko Kagaya, Hideaki Shimada, Tooru Shiratori, Mari Kuboshima, Kazue Nakashima-Fujita, Mari Yasuraoka, Takanori Nishimori, Shunsuke Kurei, Takahisa Hachiya, Akihiro Murakami, Yutaka Tamura, Fumio Nomura, Takenori Ochiai, Hisahiro Matsubara, Masaki Takiguchi and Takaki Hiwasa
    Citation: Proteome Science 2011 9:31
    Content type: Research Published on:

  20. Mass spectrometry-based proteomics has reached a stage where it is possible to comprehensively analyze the whole proteome of a cell in one experiment. Here, the employment of stable isotopes has become a stand...

    Authors: Stefan P Albaum, Hannes Hahne, Andreas Otto, Ute Haußmann, Dörte Becher, Ansgar Poetsch, Alexander Goesmann and Tim W Nattkemper
    Citation: Proteome Science 2011 9:30
    Content type: Methodology Published on:

  21. Proteomic research in the field of parathyroid tissues is limited by the very small dimension of the glands and by the low incidence of cancer lesions (1%). Formalin-fixed paraffin-embedded (FFPE) tissue speci...

    Authors: Elena Donadio, Laura Giusti, Filomena Cetani, Ylenia Da Valle, Federica Ciregia, Gino Giannaccini, Elena Pardi, Federica Saponaro, Liborio Torregrossa, Fulvio Basolo, Claudio Marcocci and Antonio Lucacchini
    Citation: Proteome Science 2011 9:29
    Content type: Research Published on:

  22. In vitro maturation (IVM) of mammalian oocytes is divided into the GV (germinal vesicle stage), MI (metaphase I stage) and MII (metaphase II stage) stages, and only fully mature oocytes have acquired the abili...

    Authors: Jumi Kim, Ji-Su Kim, Young-Joo Jeon, Dong-Wook Kim, Tae-Ho Yang, Yunjo Soh, Hak Kyo Lee, Nag-Jin Choi, Soo-Bong Park, Kang Seok Seo, Hyung Min Chung, Dong-Seok Lee and Jung-Il Chae
    Citation: Proteome Science 2011 9:28
    Content type: Research Published on:

  23. An encouraging approach for the diagnosis and effective therapy of immunological pathologies, which would include cancer, is the identification of proteins and phosphorylated proteins. Disease proteomics, in p...

    Authors: Elena López, Isabel López, Antonio Ferreira and Julia Sequí
    Citation: Proteome Science 2011 9:27
    Content type: Review Published on:

    The Retraction Note to this article has been published in Proteome Science 2013 11:16

  24. Strawberries (Fragaria ananassa) reproduce asexually through stolons, which have strong tendencies to form adventitious roots at their second node. Understanding how the development of the proximal (I-1) and dist...

    Authors: Xianping Fang, Huasheng Ma, Dezhao Lu, Hong Yu, Wenguo Lai and Songlin Ruan
    Citation: Proteome Science 2011 9:26
    Content type: Research Published on:

  25. Atherosclerosis is considered the major cause of the dramatic increase in cardiovascular mortality among patients suffering from chronic kidney disease (CKD). Although the close connection between atherosclero...

    Authors: Magdalena Luczak, Dorota Formanowicz, Elzbieta Pawliczak, Maria Wanic-Kossowska, Andrzej Wykretowicz and Marek Figlerowicz
    Citation: Proteome Science 2011 9:25
    Content type: Research Published on:

  26. High abundance protein depletion is a major challenge in the study of serum/plasma proteomics. Prior to this study, most commercially available kits for depletion of highly abundant proteins had only been test...

    Authors: Bin Liu, Fang-hua Qiu, Courtney Voss, Yun Xu, Ming-zhe Zhao, Yan-xin Wu, Jing Nie and Zi-lian Wang
    Citation: Proteome Science 2011 9:24
    Content type: Research Published on:

  27. Protection of pigs by vaccination against Actinobacillus pleuropneumoniae, the causative agent of porcine pleuropneumonia, is hampered by the presence of 15 different serotypes. A DIVA subunit vaccine comprised o...

    Authors: Falk FR Buettner, Sarah A Konze, Alexander Maas and Gerald F Gerlach
    Citation: Proteome Science 2011 9:23
    Content type: Research Published on:

  28. Proteomics may help us better understand the changes of multiple proteins involved in oncogenesis and progression of prostate cancer(PCa) and identify more diagnostic and prognostic biomarkers. The aim of this...

    Authors: Chuanyu Sun, Chao Song, Zhicheng Ma, Ke Xu, Yang Zhang, Hong Jin, Shijun Tong, Weihong Ding, Guowei Xia and Qiang Ding
    Citation: Proteome Science 2011 9:22
    Content type: Research Published on:

  29. Bladder transitional cell carcinoma (BTCC) is the fourth most frequent neoplasia in men, clinically characterized by high recurrent rates and poor prognosis. Availability of urinary tumor biomarkers represents...

    Authors: Hongjie Li, Changying Li, Huili Wu, Ting Zhang, Jin Wang, Shixin Wang and Jiwu Chang
    Citation: Proteome Science 2011 9:21
    Content type: Research Published on:

  30. Surface-Enhanced Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (SELDI-TOF-MS) is a frequently used technique for cancer biomarker research. The specificity of biomarkers detected by SELDI can be...

    Authors: Pei-Sung Hsu, Yu-Shan Wang, Su-Chen Huang, Yi-Hsien Lin, Chih-Chia Chang, Yuk-Wah Tsang, Jiunn-Song Jiang, Shang-Jyh Kao, Wu-Ching Uen and Kwan-Hwa Chi
    Citation: Proteome Science 2011 9:20
    Content type: Research Published on:

  32. Serum is an ideal source of biomarker discovery and proteomic profiling studies are continuously pursued on serum samples. However, serum is featured by high level of protein glycosylations that often cause io...

    Authors: Atsuhiko Toyama, Hidewaki Nakagawa, Koichi Matsuda, Nobuhisa Ishikawa, Nobuoki Kohno, Yataro Daigo, Taka-Aki Sato, Yusuke Nakamura and Koji Ueda
    Citation: Proteome Science 2011 9:18
    Content type: Research Published on:

  33. Low-abundance proteins are difficultly observed on the two-dimensional gel electrophoresis (2-DE) maps of urine proteome, because they are usually obscured by high-abundance proteins such as albumin and immuno...

    Authors: Chih-Ming Lu, Yu-Jen Wu, Cheng-Chi Chen, Jue-Liang Hsu, Jiing-Chuan Chen, Jeff Yi-Fu Chen, Chun-Hsiung Huang and Ying-Chin Ko
    Citation: Proteome Science 2011 9:17
    Content type: Methodology Published on:

  34. Genomics, transcriptomics and proteomics of glioblastoma multiforme (GBM) have recently emerged as possible tools to discover therapeutic targets and biomarkers for new therapies including immunotherapy. It is...

    Authors: Brigitte Collet, Nathalie Guitton, Stephan Saïkali, Tony Avril, Charles Pineau, Abderrahmane Hamlat, Jean Mosser and Véronique Quillien
    Citation: Proteome Science 2011 9:16
    Content type: Research Published on:

  37. Suitable biomarkers associated with the development of delirium are still not known. Urinary proteomics has successfully been applied to identify novel biomarkers associated with various disease states, but it...

    Authors: Mark van den Boogaard, Rachel PL van Swelm, Frans GM Russel, Suzanne Heemskerk, Johannes G van der Hoeven, Rosalinde Masereeuw and Peter Pickkers
    Citation: Proteome Science 2011 9:13
    Content type: Research Published on:

  38. Total soluble proteome alterations of white rot fungus Phanerochaete chrysosporium in response to different doses (25, 50 and 100 μM) of Pb (II) were characterized by 2DE in combination with MALDI-TOF-MS.

    Authors: Volkan Yıldırım, Servet Özcan, Dörte Becher, Knut Büttner, Michael Hecker and Gülay Özcengiz
    Citation: Proteome Science 2011 9:12
    Content type: Research Published on:

  39. Avian infectious bronchitis (IB) is one of the most serious diseases of economic importance in chickens; it is caused by the avian infectious coronavirus (IBV). Information remains limited about the comparativ...

    Authors: Zhongzan Cao, Zongxi Han, Yuhao Shao, Heyuan Geng, Xiangang Kong and Shengwang Liu
    Citation: Proteome Science 2011 9:11
    Content type: Research Published on:

  40. Wheat flour is one of the world's major food ingredients, in part because of the unique end-use qualities conferred by the abundant glutamine- and proline-rich gluten proteins. Many wheat flour proteins also p...

    Authors: Frances M Dupont, William H Vensel, Charlene K Tanaka, William J Hurkman and Susan B Altenbach
    Citation: Proteome Science 2011 9:10
    Content type: Research Published on:

  41. Labeling whole Arabidopsis (Arabidopsis thaliana) plants to high enrichment with 13C for proteomics and metabolomics applications would facilitate experimental approaches not possible by conventional methods. Suc...

    Authors: Wen-Ping Chen, Xiao-Yuan Yang, Geoffrey L Harms, William M Gray, Adrian D Hegeman and Jerry D Cohen
    Citation: Proteome Science 2011 9:9
    Content type: Methodology Published on:

  42. The aqueous humor (AH), a liquid of the anterior and posterior chamber of the eye, comprises many proteins with various roles and important biological functions. Many of these proteins have not been identified...

    Authors: Miroslava Stastna, Ashley Behrens, Peter J McDonnell and Jennifer E Van Eyk
    Citation: Proteome Science 2011 9:8
    Content type: Research Published on:

  44. Transmissible spongiform encephalopathy diseases are untreatable, uniformly fatal degenerative syndromes of the central nervous system that can be transmitted both within as well as between species. The bovine...

    Authors: Margot Plews, Lise Lamoureux, Sharon LR Simon, Catherine Graham, Viola Ruddat, Stefanie Czub and J David Knox
    Citation: Proteome Science 2011 9:6
    Content type: Research Published on:

  45. Hepatitis E is endemic to resource-poor regions, where it manifests as sporadic cases and large waterborne outbreaks. The disease severity ranges from acute self-limited hepatitis with low mortality to fulmina...

    Authors: Shikha Taneja, Imran Ahmad, Somdutta Sen, Saravanan Kumar, Reena Arora, Vijay K Gupta, Rakesh Aggarwal, Krishnamoorthy Narayanasamy, Vanga S Reddy and Shahid Jameel
    Citation: Proteome Science 2011 9:5
    Content type: Research Published on:

  46. Airway surface liquid, often referred to as mucus, is a thin layer of fluid covering the luminal surface that plays an important defensive role against foreign particles and chemicals entering the lungs. Airwa...

    Authors: Mehboob Ali, Erik P Lillehoj, Yongsung Park, Yoshiyuki Kyo and K Chul Kim
    Citation: Proteome Science 2011 9:4
    Content type: Research Published on:

  47. Hair bulge progenitor cells (HBPCs) are multipotent stem cells derived from the bulge region of mice vibrissal hairs. The purified HBPCs express CD34, K15 and K14 surface markers. It has been reported that HBP...

    Authors: Winifred WY Yau, Mei Kuen Tang, Elve Chen, YaoYao, Ivan WC Wong, Henry SS Lee and Kenneth KH Lee
    Citation: Proteome Science 2011 9:3
    Content type: Research Published on:

  48. We describe a method to identify metabolites of proteins that eliminates endogenous background by using stable isotope labeled matrices. This technique allows selective screening of the intact therapeutic mole...

    Authors: Charles B Reilly, Sri H Ramarathinam, Nicholas A Williamson and Anthony W Purcell
    Citation: Proteome Science 2011 9:2
    Content type: Methodology Published on:

  49. C-reactive protein (CRP) is a predictor of cardiovascular risk. It circulates as a pentameric protein in plasma. Recently, a potential dissociation mechanism from the disc-shaped pentameric CRP (pCRP) into sin...

    Authors: Steffen U Eisenhardt, Jonathon Habersberger, Karen Oliva, Graeme I Lancaster, Mustafa Ayhan, Kevin J Woollard, Holger Bannasch, Greg E Rice and Karlheinz Peter
    Citation: Proteome Science 2011 9:1
    Content type: Research Published on:
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