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  1. Reverse phase protein arrays (RPPA) have been demonstrated to be a useful experimental platform for quantitative protein profiling in a high-throughput format. Target protein detection relies on the readout ob...

    Authors: Heiko A Mannsperger, Stefan Uhlmann, Christian Schmidt, Stefan Wiemann, Özgür Sahin and Ulrike Korf
    Citation: Proteome Science 2010 8:69
    Content type: Methodology Published on:

  2. Citrus is one of the most important and widely grown commodity fruit crops. In this study a label-free LC-MS/MS based shot-gun proteomics approach was taken to explore three main stages of citrus fruit develop...

    Authors: Ehud Katz, Mario Fon, Richard A Eigenheer, Brett S Phinney, Joseph N Fass, Dawei Lin, Avi Sadka and Eduardo Blumwald
    Citation: Proteome Science 2010 8:68
    Content type: Research Published on:

  3. Sulforaphane (SFN) is an isothiocyanate found in cruciferous vegetables that exerts anti-oxidant, anti-inflammatory, anti-cancer and radio-sensitizing activities. Nonetheless, the mechanism responsible for SFN...

    Authors: Chan-Hee Lee, Soo-Jin Jeong, Sun-Mi Yun, Ji-Hyun Kim, Hyo-Jung Lee, Kwang Seok Ahn, Suk-Hyun Won, Hyun Seok Kim, Hyo-Jeong Lee, Kyoo-Seok Ahn, Shudong Zhu, Chang-Yan Chen and Sung-Hoon Kim
    Citation: Proteome Science 2010 8:67
    Content type: Research Published on:

  4. Numerous gel-based softwares exist to detect protein changes potentially associated with disease. The data, however, are abundant with technical and structural complexities, making statistical analysis a diffi...

    Authors: Jeffrey C Miecznikowski, Senthilkumar Damodaran, Kimberly F Sellers and Richard A Rabin
    Citation: Proteome Science 2010 8:66
    Content type: Research Published on:

  5. Previous studies suggested that dietary tannin ingestion may induce changes in mouse salivary proteins in addition to the primarily studied proline-rich proteins (PRPs). The aim of the present study was to det...

    Authors: Elsa Lamy, Gonçalo Graça, Gonçalo da Costa, Catarina Franco, Fernando Capela e Silva, Elvira Sales Baptista and Ana Varela Coelho
    Citation: Proteome Science 2010 8:65
    Content type: Research Published on:

  6. Restoration of rooting competence is important for rejuvenation in Sequoia sempervirens (D. Don) Endl and is achieved by repeatedly grafting Sequoia shoots after 16 and 30 years of cultivation in vitro.

    Authors: Ing-Feng Chang, Peng-Jen Chen, Chin-Hui Shen, Tsung-Ju Hsieh, Ya-Wen Hsu, Bau-Lian Huang, Ching-I Kuo, Yu-Ting Chen, Hsiu-An Chu, Kai-Wun Yeh and Li-Chun Huang
    Citation: Proteome Science 2010 8:64
    Content type: Research Published on:

  7. Cervicovaginal fluid has an important function in the homeostasis and immunity of the lower female genital tract. Analysis of the cervicovaginal fluid proteome may therefore yield important information about t...

    Authors: Geert Zegels, Geert AA Van Raemdonck, Wiebren AA Tjalma and Xaveer WM Van Ostade
    Citation: Proteome Science 2010 8:63
    Content type: Review Published on:

  8. The removal of high-abundance proteins from plasma is an efficient approach to investigating flow-through proteins for biomarker discovery studies. Most depletion methods are based on multiple immunoaffinity m...

    Authors: Kyunggon Kim, Jiyoung Yu, Hophil Min, Hyunsoo Kim, Byungwook Kim, Hyeong Gon Yu and Youngsoo Kim
    Citation: Proteome Science 2010 8:62
    Content type: Methodology Published on:

  9. Protein biomarkers will play a pivotal role in the future of personalized medicine for both diagnosis and treatment decision-making. While the results of several pre-clinical and small-scale clinical studies h...

    Authors: C Bart Rountree, Colleen A Van Kirk, Hanning You, Wei Ding, Hien Dang, Heather D VanGuilder and Willard M Freeman
    Citation: Proteome Science 2010 8:61
    Content type: Research Published on:

  10. Sporulation, characteristic for some bacteria such as Bacillus subtilis, has not been entirely defined yet. Protein phosphatase E (PrpE) and small, acid soluble spore proteins (SASPs) influence this process. Neve...

    Authors: Katarzyna Macur, Caterina Temporini, Gabriella Massolini, Jolanta Grzenkowicz-Wydra, Michał Obuchowski and Tomasz Bączek
    Citation: Proteome Science 2010 8:60
    Content type: Research Published on:

  11. Streptomycin (SM) is a broad spectrum antibiotic and is an important component of any anti-tuberculosis therapy regimen. Several mechanisms have been proposed to explain the emergence of resistance but still o...

    Authors: Prashant Sharma, Bhavnesh Kumar, Yash Gupta, Neelja Singhal, Vishwa Mohan Katoch, Krishnamurthy Venkatesan and Deepa Bisht
    Citation: Proteome Science 2010 8:59
    Content type: Research Published on:

  12. Diagnosis of ovarian carcinoma is in urgent need for new complementary biomarkers for early stage detection. Proteins that are aberrantly excreted in the urine of cancer patients are excellent biomarker candid...

    Authors: Siti S Abdullah-Soheimi, Boon-Kiong Lim, Onn H Hashim and Adawiyah S Shuib
    Citation: Proteome Science 2010 8:58
    Content type: Research Published on:

  13. Brain capillary endothelial cells (BCECs) form the physiological basis of the blood-brain barrier (BBB). The barrier function is (at least in part) due to well-known proteins such as transporters, tight juncti...

    Authors: Gwënaël Pottiez, Barbara Deracinois, Sophie Duban-Deweer, Roméo Cecchelli, Laurence Fenart, Yannis Karamanos and Christophe Flahaut
    Citation: Proteome Science 2010 8:57
    Content type: Research Published on:

  14. Platelets are small anucleated blood particles that play a key role in the control of bleeding. Platelets need to be activated to perform their functions and participate in hemostasis. The process of activatio...

    Authors: Pavel Májek, Zuzana Reicheltová, Jana Štikarová, Jiří Suttnar, Alžběta Sobotková and Jan E Dyr
    Citation: Proteome Science 2010 8:56
    Content type: Research Published on:

  15. Citrus canker is a disease caused by Xantomonas citri subsp.citri (Xac), and has emerged as one of the major threats to the worldwide citrus crop because it affects all commercial citrus varieties, decreases the ...

    Authors: Márcia R Soares, Agda P Facincani, Rafael M Ferreira, Leandro M Moreira, Julio CF de Oliveira, Jesus A Ferro, Maria IT Ferro, Rogério Meneghini and Fábio C Gozzo
    Citation: Proteome Science 2010 8:55
    Content type: Research Published on:

  16. The formation of the molluscan shell is regulated to a large extent by a matrix of extracellular macromolecules that are secreted by the shell forming tissue, the mantle. This so called "calcifying matrix" is ...

    Authors: Benjamin Marie, Arul Marie, Daniel J Jackson, Lionel Dubost, Bernard M Degnan, Christian Milet and Frédéric Marin
    Citation: Proteome Science 2010 8:54
    Content type: Research Published on:

  17. Prion diseases are fatal neurodegenerative disorders that accompany an accumulation of the disease-associated form(s) of prion protein (PrPSc) in the central nervous system. The neuropathological changes in the b...

    Authors: Fumiko Shinkai-Ouchi, Yoshio Yamakawa, Hideyuki Hara, Minoru Tobiume, Masahiro Nishijima, Kentaro Hanada and Ken'ichi Hagiwara
    Citation: Proteome Science 2010 8:53
    Content type: Research Published on:

  19. The extracellular proteome or secretome of symbiotic bacteria like Rhizobium etli is presumed to be a key element of their infection strategy and survival. Rhizobia infect the roots of leguminous plants and estab...

    Authors: Niurka Meneses, Guillermo Mendoza-Hernández and Sergio Encarnación
    Citation: Proteome Science 2010 8:51
    Content type: Research Published on:

  20. Currently, presence of Moraxella sp. in internal organs of fish is not considered detrimental for fish farming. However, bacterial colonization of internal organs can affect fish wellness and decrease growth rate...

    Authors: Maria Filippa Addis, Roberto Cappuccinelli, Vittorio Tedde, Daniela Pagnozzi, Iolanda Viale, Mauro Meloni, Fulvio Salati, Tonina Roggio and Sergio Uzzau
    Citation: Proteome Science 2010 8:50
    Content type: Research Published on:

  21. The nematode Caenorhabditis elegans is both sensitive and tolerant to hypoxic stress, particularly when the evolutionarily conserved hypoxia response pathway HIF-1/EGL-9/VHL is involved. Hypoxia-induced changes i...

    Authors: Hualing Li, Changhong Ren, Jinping Shi, Xingyi Hang, Feilong Zhang, Yan Gao, Yonghong Wu, Langlai Xu, Changsheng Chen and Chenggang Zhang
    Citation: Proteome Science 2010 8:49
    Content type: Research Published on:

  22. Enterococci have emerged as the third most common cause of nosocomial infections, requiring bactericidal antimicrobial therapy. Although vancomycin resistance is a major problem in clinics and has emerged in a...

    Authors: Hajer Radhouani, Patrícia Poeta, Luís Pinto, Júlio Miranda, Céline Coelho, Carlos Carvalho, Jorge Rodrigues, María López, Carmen Torres, Rui Vitorino, Pedro Domingues and Gilberto Igrejas
    Citation: Proteome Science 2010 8:48
    Content type: Research Published on:

  23. Steroid-induced adipogenesis increases fat-cell volume and pressure in bone marrow. This may be a contributing factor in some forms of osteonecrosis. In this observational study, we aimed to determine the prot...

    Authors: Sing Chung Li, Ching Yu Lin, Tzong Fu Kuo, Yun Ho Lin, Chia Chun Chen, Way Neng Lin and Wing P Chan
    Citation: Proteome Science 2010 8:47
    Content type: Research Published on:

  24. The phytopathogenic fungus Diplodia seriata, whose genome remains unsequenced, produces severe infections in fruit trees (fruit blight) and grapevines. In this crop is recognized as one of the most prominent path...

    Authors: Rebeca Cobos, Carlos Barreiro, Rosa María Mateos and Juan-José R Coque
    Citation: Proteome Science 2010 8:46
    Content type: Research Published on:

  25. The silkworm Bombyx mori is a lepidopteran insect with four developmental stages: egg, larva (caterpillar), pupa, and adult. The hemolymph of the silkworm is in an open system that circulates among all organs, an...

    Authors: Yong Hou, Yong Zou, Fei Wang, Jing Gong, Xiaowu Zhong, Qingyou Xia and Ping Zhao
    Citation: Proteome Science 2010 8:45
    Content type: Research Published on:

  26. Growth cessation, cold acclimation and dormancy induction in grapevines and other woody perennial plants native to temperate continental climates is frequently triggered by short photoperiods. The early induct...

    Authors: Kim J Victor, Anne Y Fennell and Jérôme Grimplet
    Citation: Proteome Science 2010 8:44
    Content type: Research Published on:

  27. Ticks are vectors of pathogens that affect human and animal health worldwide. Proteomics and genomics studies of infected ticks are required to understand tick-pathogen interactions and identify potential vacc...

    Authors: Margarita Villar, Alessandra Torina, Yolanda Nuñez, Zorica Zivkovic, Anabel Marina, Angela Alongi, Salvatore Scimeca, Giuseppa La Barbera, Santo Caracappa, Jesús Vázquez and José de la Fuente
    Citation: Proteome Science 2010 8:43
    Content type: Research Published on:

  28. Lipoproteins are complex, globular molecules which play essential roles in the transport and metabolism of cholesterol. Their implication in the development of cardiovascular diseases, such as atherosclerosis,...

    Authors: Lisamarie A Collins and Michael Olivier
    Citation: Proteome Science 2010 8:42
    Content type: Research Published on:

  29. Most biological functions controlled by the brain and their related disorders are closely associated with activation in specific regions of the brain. Neuroproteomics has been applied to the analysis of whole ...

    Authors: Tomoki Katagiri, Naoya Hatano, Masamune Aihara, Hiroo Kawano, Mariko Okamoto, Ying Liu, Tomonori Izumi, Tsuyoshi Maekawa, Shoji Nakamura, Tokuhiro Ishihara, Mutsunori Shirai and Yoichi Mizukami
    Citation: Proteome Science 2010 8:41
    Content type: Research Published on:

  30. Mass spectrometry and proteomic analyses have become powerful tools for the analysis of proteins and peptides. Investigation of proteins contained in the various layers of the avian eggshell has focused entire...

    Authors: Steven J Portugal, Helen J Cooper, Cleidiane G Zampronio, Laine L Wallace and Phillip Cassey
    Citation: Proteome Science 2010 8:40
    Content type: Methodology Published on:

  31. Viral and bacterial diseases can cause mass mortalities in commercial shrimp aquaculture. In contrast to studies on the antiviral response, the responses of shrimps to bacterial infections by high throughput t...

    Authors: Kunlaya Somboonwiwat, Vorrapon Chaikeeratisak, Hao-Ching Wang, Chu Fang Lo and Anchalee Tassanakajon
    Citation: Proteome Science 2010 8:39
    Content type: Research Published on:

  32. During and following myocardial ischemia, glucose oxidation rates are low and fatty acids dominate as a source of oxidative metabolism. This metabolic phenotype is associated with contractile dysfunction durin...

    Authors: Clifford DL Folmes, Grzegorz Sawicki, Virgilio JJ Cadete, Grant Masson, Amy J Barr and Gary D Lopaschuk
    Citation: Proteome Science 2010 8:38
    Content type: Research Published on:

  33. Enterococcus faecalis is an opportunistic pathogen and one of the most important causes of hospital infections. Bile acids are a major stress factor bacteria have to cope with in order to colonize and survive in...

    Authors: Liv Anette Bøhle, Ellen M Færgestad, Eva Veiseth-Kent, Hilde Steinmoen, Ingolf F Nes, Vincent GH Eijsink and Geir Mathiesen
    Citation: Proteome Science 2010 8:37
    Content type: Research Published on:

  34. Reverse phase protein arrays (RPPA) emerged as a useful experimental platform to analyze biological samples in a high-throughput format. Different signal detection methods have been described to generate a qua...

    Authors: Jan C Brase, Heiko Mannsperger, Holger Fröhlich, Stephan Gade, Christian Schmidt, Stefan Wiemann, Tim Beissbarth, Thorsten Schlomm, Holger Sültmann and Ulrike Korf
    Citation: Proteome Science 2010 8:36
    Content type: Methodology Published on:

  35. Proteomic analysis of laticifer latex in Hevea brasiliensis has been received more significant attentions. However, the sticky and viscous characteristic of rubber latex as cytoplasm of laticifer cells and the co...

    Authors: Xuchu Wang, Minjing Shi, Xiuli Lu, Ruifeng Ma, Chenggong Wu, Anping Guo, Ming Peng and Weimin Tian
    Citation: Proteome Science 2010 8:35
    Content type: Methodology Published on:

  36. Surfactant protein-A (SP-A) has been shown to play a variety of roles related to lung host defense function. Mice lacking SP-A are more susceptible to infection than wild type C57BL/6 mice. We studied bronchoa...

    Authors: Mehboob Ali, Todd M Umstead, Rizwanul Haque, Anatoly N Mikerov, Willard M Freeman, Joanna Floros and David S Phelps
    Citation: Proteome Science 2010 8:34
    Content type: Research Published on:

  38. Protein-based microarray platforms offer considerable promise as high-throughput technologies in proteomics. Particular advantages are provided by self-assembling protein microarrays and much interest centers ...

    Authors: Xristo Zárate, David C Henderson, Keenan C Phillips, April D Lake and David W Galbraith
    Citation: Proteome Science 2010 8:32
    Content type: Methodology Published on:

  39. Ovarian cancer is the most lethal gynecologic malignancy, with the majority of cases diagnosed at an advanced stage when treatments are less successful. Novel serum protein markers are needed to detect ovarian...

    Authors: Kristin LM Boylan, John D Andersen, Lorraine B Anderson, LeeAnn Higgins and Amy PN Skubitz
    Citation: Proteome Science 2010 8:31
    Content type: Research Published on:

  40. Shigella flexneri is a gram-negative, facultative pathogen that causes the majority of communicable bacterial dysenteries in developing countries. The virulence factors of S. flexneri have been shown to be produ...

    Authors: Ge Zhao, Li Zhu, Erling Feng, Xiaoyu Cao, Na Shang, Xiankai Liu, Xiang Liao, Tianyi Ying, Jie Wang, Huipeng Chen and Hengliang Wang
    Citation: Proteome Science 2010 8:30
    Content type: Research Published on:

  41. Infectious bronchitis virus (IBV) is the coronavirus of domestic chickens causing major economic losses to the poultry industry. Because of the complexity of the IBV life cycle and the small number of viral st...

    Authors: Qingming Kong, Chunyi Xue, Xiangpeng Ren, Chengwen Zhang, Linlin Li, Dingming Shu, Yingzuo Bi and Yongchang Cao
    Citation: Proteome Science 2010 8:29
    Content type: Research Published on:

  42. Hepatitis B virus (HBV) is a major cause of liver infection in human. Because of the lack of an appropriate cell culture system for supporting HBV infection efficiently, the cellular and molecular mechanisms o...

    Authors: Yanfeng Zhao, Haijing Ben, Su Qu, Xinwen Zhou, Liang Yan, Bin Xu, Shuangcheng Zhou, Qiang Lou, Rong Ye, Tianlun Zhou, Pengyuan Yang and Di Qu
    Citation: Proteome Science 2010 8:28
    Content type: Research Published on:

  43. Osteoarthritis (OA) is characterized by degeneration of articular cartilage. Animal models of OA induced are a widely used tool in the study of the pathogenesis of disease. Several proteomic techniques for sel...

    Authors: Elizabeth Pérez, José L Gallegos, Leticia Cortés, Karla G Calderón, José C Luna, Febe E Cázares, María C Velasquillo, Juan B Kouri and Fidel C Hernández
    Citation: Proteome Science 2010 8:27
    Content type: Research Published on:

  44. Flavobacterium columnare causes columnaris disease in cultured and wild fish populations worldwide. Columnaris is the second most prevalent bacterial disease of commercial channel catfish industry in the United ...

    Authors: Pradeep R Dumpala, Nagihan Gülsoy, Mark L Lawrence and Attila Karsi
    Citation: Proteome Science 2010 8:26
    Content type: Research Published on:

  45. Metamorphosis in the bryozoan Bugula neritina (Linne) includes an initial phase of rapid morphological rearrangement followed by a gradual phase of morphogenesis. We hypothesized that the first phase may be indep...

    Authors: Yue Him Wong, Shawn M Arellano, Huoming Zhang, Timothy Ravasi and Pei-Yuan Qian
    Citation: Proteome Science 2010 8:25
    Content type: Research Published on:

  46. Often high-quality MS/MS spectra of tryptic peptides do not match to any database entry because of only partially sequenced genomes and therefore, protein identification requires de novo peptide sequencing. To ac...

    Authors: Stephan Jung, Claudia Fladerer, Frank Braendle, Johannes Madlung, Otmar Spring and Alfred Nordheim
    Citation: Proteome Science 2010 8:24
    Content type: Research Published on:

  47. Gel-based proteomic is the most popular and versatile method of global protein separation and quantification. This is a mature approach to screen the protein expression at the large scale, and a cheaper approa...

    Authors: François Chevalier
    Citation: Proteome Science 2010 8:23
    Content type: Review Published on:

  48. Poly(ADP-ribose) polymerases (PARPs) catalyze the formation of poly(ADP-ribose) (pADPr), a post-translational modification involved in several important biological processes, namely surveillance of genome inte...

    Authors: Maxim Isabelle, Xavier Moreel, Jean-Philippe Gagné, Michèle Rouleau, Chantal Ethier, Pierre Gagné, Michael J Hendzel and Guy G Poirier
    Citation: Proteome Science 2010 8:22
    Content type: Research Published on:

  50. Mulberry dwarf (MD), which is caused by phytoplasma, is one of the most serious infectious diseases of mulberry. Phytoplasmas have been associated with diseases in several hundred plant species. The inability ...

    Authors: Xianling Ji, Yingping Gai, Baoyun Lu, Chengchao Zheng and Zhimei Mu
    Citation: Proteome Science 2010 8:20
    Content type: Research Published on:
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ISSN: 1477-5956