Fig. 2

Volcano plots of the–log₁₀ (p-value) versus the log₂ fold change of peptide intensity, to compare groups a two-sample Student’s T-Test with a 0.05 false discovery rate (FDR) is used to indicate significance between given groups. Significant values (p-value < 0,05) are indicated as filled circles (blue) and (p-value < 0.01) filled (red) squares. The total overview of all significant proteins can be found in supplemental file 3. (A) T-test with CVD compared to without CVD (239 sign. proteins), (B) paired T-test Before CVD group compared to After CVD (74 sign. proteins), (C) T-test before CVD compared to control group (236 sign. proteins), (D) T-test After CVD compared to control group (150 significant proteins)