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Table 1 The differential proteins regulated by HIV-1 proteins, involved in the immune system, and located in plasma membrane

From: iTRAQ-based proteomic study on monocyte cell model discovered an association of LAMP2 downregulation with HIV-1 latency

Accession #

Unused

% Cov

Name

Gene name

Peptides − 95%

Fold change

p-value

*Regulated by HIV proteins

P63010

85.19

63.2

AP-2 complex subunit beta

AP2B1

101

2.03

1.88E-02

Tat

P16671

17.97

28.6

Platelet glycoprotein 4

CD36

21

0.2

1.62E-04

Nef/gp41

P01730

10.64

29.9

T-cell surface glycoprotein CD4

CD4

6

0.31

7.80E-03

Nef/gp120//Vpu/Vpr/gp160/gp120

P04839

21.95

34.2

Cytochrome b-245 heavy chain

CYBB

23

0.28

1.30E-03

Capsid/Tat

P06734

10.26

38.3

Low affinity immunoglobulin epsilon Fc receptor

FCER2

9

0.18

2.53E-04

gp120

P09769

18.17

38.6

Tyrosine-protein kinase Fgr

FGR

14

0.43

1.20E-03

gp120

P04439

55.19

70.7

HLA class I histocompatibility antigen, A-3 alpha chain

HLA-A

111

0.38

7.54E-04

Nef/Vpu/Tat

P10809

38.97

45.2

60 kDa heat shock protein, mitochondrial

HSPD1

24

2.32

1.55E-02

Tat

P23229

58.91

39.3

Integrin alpha-6

ITGA6

39

0.47

1.11E-03

Vif

Q6GTX8

15.93

39

Leukocyte-associated immunoglobulin-like receptor 1

LAIR1

13

0.19

2.93E-03

Nef

P13473

10.43

22

Lysosome-associated membrane glycoprotein 2

LAMP2

12

0.44

1.63E-02

Vpu/Nef

P04156

4

12.7

Major prion protein

PRNP

4

0.36

3.66E-03

Nucleocapsid

P02786

75.62

64

Transferrin receptor protein 1

TFRC

117

3.34

1.53E-04

Vpr

P08670

58.98

54.5

Vimentin

VIM

51

0.37

2.32E-04

Vpr

  1. # from UniProtKB database