Fig. 1

Isolation and characterization of exosomes. A Schematic flow of exosome isolation. B Transmission electron microscopy of exosomes from CHMp and CHMm cells. Exosomes are negative stained. Isolated exosomes show a cup-shaped morphology. Scale bar: 200 nm. C Dynamic light scattering analysis of CHMp and CHMm-derived exosomes. The mean diameter size of CHMp-derived exosomes were 91.6 ± 17.5 nm and CHMm-derived exosomes were 33.0 ± 0.0 nm