Fig. 3

Gene mutation features and gene set enrichment analysis in TCGA-LIHC datasets. A-B Comparison of TMB (A) and number of mutated genes (B) between low- and high-risk groups. Student t test was conducted. C The waterfall diagram visualizing the top 10 mutated genes in the two risk groups (P < 0.05). Chi-square test was performed. D Enriched four KEGG pathways in low-risk group assessed by gene set enrichment analysis. TMB, tumor mutation burden. ES, enrichment score. NES, normalized enrichment score. FDR, false discovery rate. ns, no significance