Figure 3
From: Modeling regionalized volumetric differences in protein-ligand binding cavities

Estimating p -values. Estimating the probability p of observing a fragment F', with volume v(F') ≥ v(F), using the mean () and variance (s) of the distribution of the log-transformed sample values to estimate µ and σ. Φ is the cumulative distribution function of the standard normal distribution.